科技论文和展示

这里您可以找到在全球 COMSOL 年会上所有用户报告的演示文稿。这些演示文稿介绍 COMSOL 用户是如何使用 COMSOL Multiphysics 进行创新性研究和产品设计。研究主题涵盖了包括电气、机械、流体和化工等范围广泛的行业和应用领域。请使用“快速搜索”来查找与您的研究领域相关的演示文稿。

Biosimulation of Normal Pressure Hydrocephalus Using COMSOL Multiphysics®

K. Shahim[1], J-M. Drezet[1], J-F. Molinari[2], S. Momjian[3], and R. Sinkus[4]

[1]LSMX, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
[2]LSMS, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
[3]University Hospitals of Geneva and University of Geneva, Switzerland
[4]Waves and Acoustics Laboratory, ESPCI, Paris, France

A numerical finite element model of one human brain is built in COMSOL in order to study a particular form of hydrocephalus, the so called Normal Pressure Hydrocephalus (NPH). The geometry of the ventricles and the skull is obtained by Magnetic Resonance Imaging (MRI) and imported in COMSOL Multiphysics. Form the mechanical point of view, the brain parenchyma is modeled as a porous medium fully ...

Estimating Cerebral Blood Flow using Electro-mechanical Modeling and Impedance Tomography Measurements

A. Jeremic, and T. Gadkari
McMaster University, Hamilton, ON, Canada

In this paper we propose a coupled electromechanical finite element model which combines the Navier-Stokes Equations of blood flow in an immersed boundary and the resulting deformed geometry with an electromagnetic model, which describes the electric field in the presence of deformation/structure changes caused by the blood flow in arteries.We derive least-squares estimates of the pressure drop ...

Some Clinical and Computational Studies On Haemodynamics In Stenosed Artery

A. Chanda, A.R. Choudhury, G. Ray, K. Dasgupta, and D. Nag
Jadavpur University, Kolkata, West Bengal, India

Atherosclerosis in arteries is caused by the formation of stenosis : fatty depositions, on the artery wall. In current medicine, the practice is to observe the maximum percentage occlusion at any arbitrary cross-section and diagnose the patient on that basis, which might not always present the real picture due to non-uniformity of the stenosis thickness. The present work attempts to simulate the ...

A Biological Gear in the Human Middle Ear

H. Cai, R.P. Jackson, C. Steele, and S. Puria
Stanford University, Stanford, CA, USA

To support high frequency transmission, the mammalian middle ear construction is unique. The middle ear bones are connected through two mobile joints, the malleus-incus joint (MIJ) and the incudostapedial joint (ISJ). These synovial joints, consisting of joint capsule and synovial fluid inside, play an important role in sound transmission. We developed our current FE model using COMSOL that ...

Large Scale Invasion Of New Species And Of Genetic Information

O. Richter, F. Suhling, and S. Moenickes
Technische Universität Braunschweig, Germany

The spatial dynamics of the invasion of new species and genetic dispersal is studied under the presumption of rising temperature by using a coherent approach of coupled partial differential equations of the reaction diffusion type. The nonlinear reaction terms model the population dynamics, genetic exchange and competition. Temperature reaction norms of reproduction rates are conferred by a two ...

Local Electroporation of Single Adherent Cells by Micro-Structured Needle Electrodes

K. K. Sriperumbudur[1], P. J. Koester[1], M. Stubbe[1], C. Tautorat[1], J. Held[2], W. Baumann[1], and J. Gimsa[1]
[1] University of Rostock, Chair of Biophysics, Gertrudenstr. 11a, 18057 Rostock, Germany
[2] Microsystem Material Laboratory, Department of Microsystems Engineering (IMTEK), University of Freiburg, Germany

In spite of its low throughput, Patch-Clamp is the established method for intracellular measurements of the transmembrane potential. To address this problem, we have developed new biosensor-chips with micro-structured needle electrodes (MNEs). MNE-penetration of single cells growing on the MNE-tips leads to a situation comparable to the whole-cell mode in classical Patch Clamp. MNE-penetration ...

Designing an Array of Nanocalorimeters for Screening Biochemical Interactions

F. Torres
Palo Alto Research Center

In this presentation we present our analysis of the PARC Nanocalorimeter. Calorimetry is basically the measuring of heat of chemical reactions or physical changes. Nanocalorimetry is Calorimetry at the Nanometer scale. The PARC Nanocalorimeter is a special type of Calorimeter, it consists of arrays of Nanocalorimeters. The PARC Nanocalorimeter is intended to be used for screening biochemical ...

A Mean Field Approach to Many-particles Effects in Dielectrophoresis

O. Nicotra, and A. La Magna
CNR-IMM Sezione di Catania, Catania, Italy

One of the major applications for dielectrophoresis is the selective trapping and fractionation in lab-on-a-chip devices. Nevertheless, many-particle effects due to high concentrations of biological material around electrodes can cause a rapid decrease of trapping efficiency in dielectrophoretic devices. In this contribution we present a new approach based on a drift-diffusion dynamics to study ...

Finite Element Analysis Approach for Optimization of Enzyme Activity for Enzymatic Bio-fuel Cell

Y. Song, and C. Wang
Florida International University, Miami, FL, USA

Enzymatic biofuel cells (EBFCs) are miniature, implantable power sources, which use enzymes as catalysts to perform redox reaction with biological fuels such as glucose. In this study using COMSOL Multiphysics, we use an EBFC chip, having three dimensional, highly dense micro-electrode arrays, fabricated by C-MEMS micro-fabrication techniques. Glucose oxidase (GOx) is immobilized on anodes for ...

Singlet Oxygen Modeling of BPD Mediated-PDT Using COMSOL

T.C. Zhu[1], B. Liu[1], X. Liang[1]
[1]University of Pennsylvania, Philadelphia, PA, USA

Singlet oxygen (1O2) is the major cytotoxic agent during photodynamic therapy (PDT). A previously developed model that incorporates the diffusion equation for the light transport in tissue and the macroscopic kinetic equations for the generation of the singlet oxygen, can be used to numerically calculate the distance-dependent reacted 1O2 using finite-element method (FEM). The formula of reacted ...

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