Simulation of Chemotractant Gradients in Microfluidic Channels to Study Cell Migration Mechanism in Silico
P. Wallin, E. Bernson, J. Gold
Chalmers University of Technology, Applied Physics, Biological Physics, Gothenburg, Sweden
Cell migration of endothelial cells along gradients is an important process in vivo and an interesting target for cancer therapeutics. Microfluidics offer very powerful tools to study such migration processes in detail in the lab. In this study, we describe a model to simulate molecular gradients in a diffusion based microfluidic gradient generator and how a cell senses these gradients via cell ...
University of Turku, Turku, FInland
An experimental LED light composed of a multi-chip LED-module, a LED driver and an efficient heat sink, was investigated using COMSOL Multiphysics software and the Heat Transfer Module. In an LED light heat is mainly generated in the LEDs but some amount of heat is generated also in the LED driver. The main target of the simulations was to resolve the junction temperatures of LEDs, the most ...
V. Pavelko, I. Pavelko, M. Smolyaninovs, H. Pffeifer, M. Wevers
Riga Technical University, Riga, Latvia
Catholic University Leuven, Leuven, Belgium
A problem of damage prediction in aircraft structure and its non-destructive evaluation is very important for aircraft structural health assessment. The analysis of the features of direct impact of thin-walled laminate component of aircraft was performed by COMSOL Multiphysics software. Mainly the GFRC and CFRC laminates were selected in form either thin separate plate or sandwich structure. The ...
H. Bruus, P.B. Muller, R. Barnkob, M.J.H. Jensen
Technical University of Denmark, Kongens Lyngby, Denmark
COMSOL, Kongens Lyngby, Denmark
We have simulated the ultrasound-induced acoustophoretic motion of microparticles suspended in an aqueous solution. The full first-order thermoviscous acoustics equations have been implented on a rectangular microfluidic 2D domain excited with an ultrasound field tuned to resonance near 2 MHz. The micrometer-thin but crucial viscous boundary layers at the rigid walls have been fully resolved. The ...
T. Andersen, M. A. E. Andersen, O. C. Thomsen
DTU Elektro, Technical University of Denmark, Kgs. Lyngby, Denmark
In this work COMSOL is utilized to obtain the Mason lumped parameter model for a piezoelectric transformer (PT) design. The Mason lumped parameters are relevant in the design process of power converters. The magnitude of the impedance is simulated for a specific interleaved multilayer thickness mode PT. The PT design has been prototyped and the measurements results are compared with simulations. ...
A Parametric Study on the Dynamic Behavior of Cable Supported Bridges Under Moving Loads Affected by Accidental Failure Mechanisms
P. Lonetti, A. Pascuzzo, R. Sarubbo
Department of Structural Engineering, University of Calabria, Rende, Cosenza, Italy
The dynamic behavior of cable supported bridges subjected to moving loads and affected by corrosion and accidental failure mechanism in the cable suspension system is investigated. The different types of cable supported bridges are distinctively characterized by the configuration of the cable system . The suspension system comprises a parabolic main cable and vertical hanger cables connecting ...
A. Castellano, P. Foti, A. Fraddosio, S. Marzano, M.D. Piccioni, D. Scardigno
DICAR, Politecnico di Bari, Bari, Italy
Introduction: Improving the capability of nondestructive evaluations requires the analysis of suitable models dealing with the physical and mechanical phenomena involved in the experiments. For example, ultrasonic tests may be a powerful, fast and effective method for nondestructive characterization of mechanical properties of materials. This requires the study of the related elastodynamic ...
M. Berger, W. Schernus
West Coast University of Applied Sciences, Heide, Germany
Results presented are a contribution to the design of a 5kW-DC-AC-converter for applications in forklifts. The device is located in a closed environment and entirely operated with passive cooling. Due to concurrent engineering approach and environmental conditions correct prediction of absolute temperature values by simulation was crucial. Heat sinks have been modeled properly and a thermal ...
B. Hagemann, J. Wegner, L. Ganzer
Clausthal University of Technology, Clausthal-Zellerfeld, Germany
In tight gas formations where the low matrix permeability prevents successful and economic production rates, hydraulic fracturing is required to produce a well at economic rates. As production from the well and its initial fracture declines, re-fracturing treatments are required to accelerate recovery. The orientation of the following hydraulic fracture depends on the actual stress-state of the ...
D. Iber, D. Menshykau
D-BSSE, ETH Zurich, Basel, Switzerland
Organogenesis is a tightly regulated process that has been studied experimentally for decades. We are developing mechanistic models for the morphogenesis of limbs, lungs, and kidneys with a view to integrate available knowledge and to better understand the underlying regulatory logic. Organ size changes dramatically during development, and tissues are composed of several layers that may expand ...